EFFECT OF REGULAR AEROBIC PHYSICAL LOAD ON THE MORPHOMETRIC INDICATORS OF THE VISCERAL AND SUBCUTANIAL FAT TISSUE OF RATS

DOI: https://doi.org/10.29296/24999490-2019-05-06

I.Yu. Yakimovich(1), S.V. Gusakova(1), M.Yu. Kotlovsky(1), V.V. Ivanov(1), V.N. Vasilyev(1), A.M. Dygai(2), D.A. Kudlay(3) 1-Siberian State Medical University, Moscow Road, 2, Tomsk, 634050, Russian Federation; 2-Goldberg Research Institute of Pharmacology and Regenerative Medicine, Lenin Prospect, 3, Tomsk, 634028, Russian Federation; 3-State Research Center «Institute of Immunology» of the Federal Medical-Biological Agency, Kashirskoye sh., 24, Moscow, 115522, Russian Federation E-mail: [email protected]

Introduction. Excess and lack of adipose tissue are associated with a violation of its functions, the mass of adipose tissue and its distribution play an important role in the development of metabolic disorders. The study of the influence of the main factors of influence on adipose tissue – nutrition and physical activity are topical issues. The aim of the study. To assess the effect of aerobic exercise on the morphometric parameters of white adipose tissue of rats on the background of increased caloric intake (with a predominance of vegetable and animal fat in the diet). Methods. The experimentations were carried out on 64 male Wistar rats. Rats’ body mass, body length, body mass index, lean mass, specific weight of adipose tissue were estimated, adipocyte size. Results. Aerobic physical activity provided with high-calorie diet resulted in decrease of body mass, body mass index, lean mass and adipose tissue density. Abovementioned parameters changed proportionally in the group of animals with animal fat prevalence in nutrition, whereas more expressed decrease of adipose tissue mass due to subcutaneous fat was discovered in the group of animals with vegetable fat prevalence in nutrition. Reduction of adipocytes average size was observed with same prevalence in all adipose depots provided with animal fat prevalence nutrition. Reduction of average size of adipocytes of retroperitoneal and mesenteric adipose depots, provided with vegetable fat prevalence nutrition. Conclusion. Physical activity greatly influenced adipose tissue mass, qualitative and quantitative changes of average size of adipocytes in adipose depots are more effective provided with high vegetable fat content nutrition.
Keywords: 
physical activity, adipose tissue, adipocytes, diet, vegetable fats, animal fats
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