IMMUNOCYTOCHEMISTRY OF THE BUCCAL EPITHELIUM:OPTIMISATION OF DIAGNOSTICS OF BREST CANCER

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S.S. Konovalov (1), O.M. Litviakova (1), N.S. Linkova (1), E.V. Sedov (1), T.V. Kvetnaia (1), S.U. Mursalov (1), A.O. Durnova (2), G.Kh. Tolibova (2), A.V. Kostylev (1)
1 -Saint-Petersburg Institute of Bioregulation and Gerontology,
2 -Federal State Budgetary Institution «The Research Institute of Obstetrics and Gynecology named after D.O. Ott» of the North-West Branch of the Russian Academy of Medical Sciences

The expression of signal molecules RON, CD90, CD73, СD64, Pax6, Chx10, RTF1, Oct2, which characterized the status of local and system homeostasis have been verified in the buccal epithelium from women with breast cancer. The most important markers, correlated with probability of oncology are the factors of anticancer protection CD64 and RON as well as molecules of terminal cells differentiation Oct2 and Chx10.
Keywords: 
brest cancer, buccal epithelium, signal molecules