AORTIC ANEURYSMS: ETIOLOGY AND PATHOMORPHOLOGY

DOI: https://doi.org/None

E.M. Paltseva B.V. Petrovsky Russian Surgery Research Center, Moscow, Russia Abrikosovskiy by-street, 2, Moscow, Russian Federation, 119991

The etiologic factors, features of pathogenesis and pathomorphology of thoracic and abdominal aortic aneurysms are considered in review. The morphologic and biologic features of the wall of thoracic aneurysms in Marfan's disease, Ehlers-Danlos, Loeys-Dietz, Turner and Noonan syndromes, aortic coarctation, bicuspid aortic valve, arterial hypertension, Takayasu arteritis, aneurysms of infectious nature are described. The data about the role of the artery wall cells, different extracellular matrix components and proteinases degrading them as well as etiologic factors in the formation of abdominal aortic aneurisms are provided.
Keywords: 
thoracic aortic aneurysm, abdominal aortic aneurysm, cystic medial degeneration, elastic fibers, collagen fibers, proteinases, inflammation
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