ANALYSIS OF THE ASSOCIATION BETWEEN AIR POLLUTION AND THE DEVELOPMENT OF LARYNGOTRACHEITIS IN CHILDREN

DOI: https://doi.org/None

L.M. Stanislavchuk National Pirogov Memorial Medical University of Vinnytsia, Pirogov str., 56, Vinnytsia, 21018, Ukraine

Introduction. Ambient air pollution is important worldwide problem. Numerous studies have found associations between air pollution and respiratory diseases, cardiovascular diseases, diabetes, and infant mortality. Children are more susceptible to the air pollutants than adults. Due to various reasons the results of studies of effects of some anthropogenic pollutants on human health are not always consistent. The aim of the study was to examine the air quality in the city of Vinnytsia and to study the association between laryngotracheitis (LT) episode rates in children and daily both average concentrations and 20-minute maximum concentrations of outdoor air pollutants. Methods. There were analyzed concentrations of particulate matter, sulfur dioxide, carbon monoxide, nitrogen dioxide, hydrogen fluoride, ammonia, formaldehyde in the city of Vinnytsia during a 5-year period (2000–2004). During the observation period there was studied the number of emergency department calls due to LT occurence in children aged of 0–14 years. Results. The degree of air pollution in Vinnytsia was established to be consistently high mainly due to formaldehyde, hydrogen fluoride and particulate matter. Direct weak correlations were revealed between LT episodes and daily both average concentrations and 20-minute maximum concentrations of nitrogen dioxide and hydrogen fluoride in the air. Conclusion. Number of LT episodes in children population is related to ambient air pollution.
Keywords: 
stenotic laryngotracheitis, children, ambient air pollution

Список литературы: 
  1. World Health Organization (2006). Air quality guidelines. Global update 2005. Particulate matter, ozone, nitrogen dioxide and sulfur dioxide. Copenhagen: World Health Organization Regional Office for Europe. http://whqlibdoc.who.int/ hq/2006/WHO_SDE_PHE_OEH_06.02_eng.pdf
  2. World Health Organization (2013). Review of evidence on health aspects of air pollution – REVIHAAP Project. Technical Report. Bonn: World Health Organization European Centre for Environment and Health, Copenhagen: World Health Organization Regional Office for Europe. http://www.euro.who.int/__data/assets/pdffile/0004/193108/REVIHAAP-Final-technical-report-final-version.pdf
  3. World Health Organization (2014). Ambient (outdoor) air quality and health [Fact sheet No.313, Updated March 2014]. http://www.who.int/mediacentre/factsheets/fs313/en/
  4. World Health Organization (2013). Health risks of air pollution in Europe – HRAPIE project. New emerging risks to health from air pollution – results from the survey of experts. Copenhagen: World Health Organization Regional Office for Europe. http://www.euro.who.int/en/health-topics/environment-and-health/airquality/ publications/2013/health-risks-of-air-pollution-in-europe-hrapie-project.-new-emerging-risks-to-health-from-air-pollution-results-from-the-survey-of-experts
  5. Lin M., Stieb D.M., Chen Y. Coarse particulate matter and hospitalization for respiratory infections in children younger than 15 years in Toronto: a case-crossover analysis. Pediatrics. 2005; 116 (2): 235–40.
  6. Privalova L.I., Kosheleva A.A., Brezgina S.V. Analiz vremennyh ryadov ustanovleniya zavisimosti respiratornoy simptomatiki u detey ot kolebaniy zagryazneniya atmosfernogo vozduha. Gigiena i sanitariya. 2007; 3: 64–7.[Privalova L.I., KoshelevaA.A., Brezgina S.V., 2000: Analysis of time series to establish the relationship of respiratory symptomatology in children to ambient air pollution fluctuations. Gigiyena i Sanitariya. 2007; 3: 64–7 (in Russian)]
  7. Surzhikov V.D., Surzhikov D.V. Ocenka i upravlenie riskom dlya zdorov`ya ot mnogokomponentnogo zagryazneniya okruzhayushhey sredy krupnogo centra metallurgii. Gigiena i sanitariya. 2006; 5: 32–5.[Surzhikov V.D., Surzhikov D.V. Assessment and management of human risk due multicomponent environmental pollution in a large metallurgy center. Gigiyena i Sanitariya. 2006; 5: 32–5 (in Russian)]
  8. Brunekreef B., Beelen R., Hoek G., Schouten L., Bausch-Goldbohm S., Fischer P., Armstrong B., Hughes E., Jerrett M.,van den Brandt P. Effects of long-term exposure to traffic-related air pollution on respiratory and cardiovascular mortality in the Netherlands: the NLCS-AIR study. Res Rep Health Eff Inst. 2009; 139: 5–71.
  9. Plunkett L.M., Turnbull D., Rodricks J.V. Differences between adults and children affecting exposure assessment. In: Guzelian P.S., Henry C.J., Olin S.S., eds. Similarities and Differences Between Children and Adults: Implications for Risk Assessment. Washington, DC: ILSI Press; 1992; 79–96.
  10. Wiley J.A., Robinson J.P., Piazza T., Garrett K., Cirksena K., Cheng Y.T., Martin G. Activity Patterns of California Residents: Final Report. Sacramento, CA: California Air Resources Board; 1991; publication No. A6-177-33.
  11. Wiley J.A., Robinson J.P., Cheng Y.T., Piazza T., Stork L., Pladsen K. Study of Children’s Activity Patterns: Final Report. Sacramento, CA: California Air Resources Board; 1991; publication No. A733-149.
  12. Rebmann H., Huenges R., Wichmann H.E., Malin E.M., Hübner H.R., Röll A., Hörz G., Hub R., Walter C., Döller G. Croup and air pollutants: results of a two-year prospective longitudinal study. Zentralbl Hyg Umweltmed. 1991; 192 (2): 104–15.
  13. Karavaev V.E., Orlova S.N., Alenina T.M., Al`per I.A., Kozyreva I. I. Vliyanie e`kologo-klimaticheskih faktorov na chastotu i techenie stenoziruyushhih laringotraheitov pri ORZ u detey. Gigiena i sanitariya. 2007; 2: 7–9.[Karavaev V.E., Orlova S.N., Alenina T.M., Alper I.A., Kozyreva I.I. Influence of environmental and climatic factors on the incidence and course of stenosing laryngotracheitis in children with acute respiratory diseases. Gigiyena i Sanitariya. 2007; 2: 7–9 (in Russian)]
  14. Macintyre E.A., Gehring U., Mölter A., Fuertes E., Klümper C., Krämer U., Quass U., Hoffmann B., Gascon M., Brunekreef B., Koppelman G.H., Beelen R., Hoek G., Birk M., de Jongste J.C., Smit H., Cyrys J., Gruzieva O., Korek M., Bergström A., Agius R.M., de Vocht F., Simpson A., Porta D., Forastiere F., Badaloni C., Cesaroni G.,Esplugues A., Fernández-Somoano A., Lerxundi A., Sunyer J., Cirach M., Nieuwenhuijsen M.J., Pershagen G., Heinrich J. Air pollution and respiratory infections during early childhood: an analysis of 10 European birth cohorts within the ESCAPE project. Environ Health Perspect. 2014; 122: 107–13.
  15. Severien C., Mietens C. Effect of nitrogen oxides and suspended dust in the air on the incidence of inpatient treatment of children with stenosing laryngotracheitis (pseudocroup). Results of an 8-year epidemiologic retrospective study based on inpatient case figures and area-related data of air measurements in the Bochum city district. Monatsschr Kinderheilkd. 1987; 135 (10): 686–91.
  16. Nakaz Mіnіsterstva ohoroni zdorov’ya Ukraїni №18 vіd 04.06.2010 r. Pro zatverdzhennya znachennya gіgієnіchnogo normativu hіmіchnoї rechovini v atmosfernomu povіtrі naselenih mіsc`.[Order of the Ministry of Health of Ukraine No.18 of June 4, 2010. On approving hygienic regulations of chemical substances in the ambient air of populated areas (in Ukrainian)]
  17. Rukovodyashhiy dokument 52.04.667-2005. Dokumenty o sostoyanii zagryazneniya atmosfery v gorodah dlya informirovaniya gosudarstvennyh organov, obshhestvennosti i naseleniya. Obshhie trebovaniya k razrabotke, postroeniyu, izlozheniyu, soderzhaniyu. M.: Meteoagenstvo Rosgidrometa, 2006; 52.[Guiding document 52.04.667-2005. Documents on ambient air pollution in urban areas for informing of state authorities and public. General requirements for the development, structure, presentation and content. M.: Meteoagenstvo Rosgidrometa, 2006; 52 (in Russian)]