RADIOLOGY AND MORPHOLOGICAL COMPARISONS AT DIAGNOSTICS OF SPLENIC HAMARTOMA

DOI: https://doi.org/None

Ionkin D.A., Glotov A.V., Kalinin D.V., Stepanova Yu.A., Kosova I.A., Karelskaya N.A.

Objective to analyze own data on diagnostics, morphological verification and treatment of the splenic hamartoma, and compare them with the previous research results. Materials and Methods. More than 300 patients with various focal lesions of the spleen have been treated at the A.V. Vishnevsky Institute of Surgery, but splenic hamartoma was observed only in four cases (2 males and 2 females, 50–58 years). Medical history, ultrasonography with duplex scanning, MDCT, MRI was performed in any case. All patients were undergone to surgical treatment, neoplasms were morphologically verified by virtue of histological and immunohistochemical studies. Results. Problems of diagnosis and differential diagnostic difficulties according to ultrasound, MDCT, MRI data were described. Malignancy was suspected in three cases, that influenced on the choice of surgery extent. Spleen resection was performed in two cases. Long-term results were evaluated in all patients. No signs of tumor recurrence were found in any case. The best long-term results, including the quality of the life was observed after the spleen resection. Conclusion. Rare occurrence of splenic hamartoma largely explains the difficulties of preoperative diagnosis. Hamartoma should be included in the differential diagnosis in the case of hypervascular lesion of the spleen. In unclear cases intraoperative frozen section biopsy may help to make a correct diagnosis, which makes it possible to perform organ-preserving surgery (in case of technical opportunity) and ensure a higher quality of the life after the postoperative period. Immunohistochemical study is an important additional method of differential diagnosis of hamartoma of the spleen
Keywords: 
splenic hamartoma, radiological semiotics, morphological comparisons, surgical treatment
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