SIGNALING MOLECULES IN BUCCAL EPITHELIUM: OPTIMIZATION OF DIAGNOSIS OF SOCIALLY SIGNIFICANT DISEASES
Buccal epithelium (BE) is an easily accessible target for molecular diagnosis of various diseases, and non-invasive way to get it is
possible. This review summarizes the results of studies indicating a change in the expression of various signaling molecules and electrokinetic
characteristics of BE in pathological processes, and evaluation of a biological age of human beings. Found that the BE has been established
to be informative material in the diagnosis of a number of socially significant diseases, including immune pathology, bronchial asthma,
ulcerative colitis, Crohn's disease, tumor growth and metabolic disorders.
Keywords:
buccal epithelium, signaling molecules, molecular markers, neuroimmunoendocrine intercommunication, socially significant
diseases, biological age