КУЛЬТИВИРОВАНИЕ ТИРЕОЦИТОВ, ТИРЕОИДНЫХ ФОЛЛИКУЛОВ И МИКРООРГАННЫХ КУЛЬТУР ЩИТОВИДНОЙ ЖЕЛЕЗЫ КАК ПЕРВЫЙ ЭТАП СОЗДАНИЯ ТКАНЕИНЖЕНЕРНЫХ КОНСТРУКЦИЙ

DOI: https://doi.org/10.29296/24999490-2018-05-02

Н.С. Сергеева(1, 3), доктор биологических наук, профессор, Ю.Д. Хесуани(2), И.К. Свиридова(1), кандидат биологических наук, П.А. Каралкин(1), кандидат медицинских наук, А.П. Поляков(1), кандидат медицинских наук, В.А. Миронов(2), кандидат медицинских наук, А.Д. Каприн(1), доктор медицинских наук, профессор, академик РАН 1-Московский научно-исследовательский онкологический институт им. П.А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России, Российская Федерация, 125284, Москва, 2-й Боткинский пр., д. 3; 2-ЧУ «ЗD-Биопринтинг Солюшенс», Российская Федерация, 115409, Москва, Каширское шоссе, д. 68, корп. 2; 3-Кафедра биологии педиатрического факультета ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, Российская Федерация, 117997, Москва, ул. Островитянова, д. 1 E-mail: prognoz.06@mail.ru

Одним из путей восстановления утраченных функций щитовидной железы (в частности, в результате оперативных вмешательств) является создание ее тканеинженерных конструктов. Создание полноценных тканеинженерных конструктов требует культур функционально активных тиреоцитов, способных формировать тиреоидные фолликулы, культур тиреоидных фолликулов или микроорганных культур щитовидной железы. Разработка таких культур (моделей) является предметом исследований ряда лабораторий. В настоящем обзоре систематизированы основные итоги этих исследований.

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